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SOPHiA GENETICS SA (SOPH) Annual Reports

SOPHiA GENETICS SA is listed on Nasdaq, classified by the SEC under Services-Computer Processing & Data Preparation (SIC 7374). This page indexes 3 annual reports, each linking to the full text on the SEC's EDGAR system.

Company profile

  • Exchange: Nasdaq
  • Fiscal year end: 12/31
  • SEC CIK: 1840706 →

Website:Official site ↗

Financial Highlights

FY2025 (quarterly, ended 2025-06-30)
CurrentPrior yearYoY
Revenue $18.3M $15.8M +15.9%
Operating income $-18.5M $-15.0M -23.2%
Net income $-22.4M $-15.2M -47.5%
EPS (diluted) $-0.33 $-0.23 -43.5%

Source: SEC EDGAR (XBRL company facts)

Financial history

Revenue & profit
Quarterly · In mn (USD)
Revenue 41.2 mn Net income -39.2 mn
2019Q4 2020Q4 2021Q4 2022Q2 2022Q4 2023Q2 2023Q4 2024Q2 2024Q4 2025Q2 2025Q4
Show table:Income statement
Item2019Q42020Q42021Q42022Q22022Q42023Q22023Q42024Q22024Q42025Q22025Q4
Revenue25.4 28.4 40.5 11.7 25.0 15.1 33.4 15.8 33.6 18.3 41.2
Gross profit17.8 17.7 25.2 7.62 16.9 10.1 23.2 10.8 22.8 12.3 27.6
Operating income-37.4 -71.5 -24.1 -38.7 -20.1 -35.5 -15.0 -32.8 -18.5 -36.4
Net income-33.8 -39.3 -73.7 -24.7 -37.3 -21.4 -37.9 -15.2 -33.6 -22.4 -39.2
Balance sheet
Quarterly · In mn (USD)
Total assets 163 mn Total liabilities 116 mn
2019Q4 2020Q4 2021Q4 2022Q2 2022Q4 2023Q2 2023Q4 2024Q2 2024Q4 2025Q2 2025Q4

Equity = assets − liabilities. Balance-sheet figures are period-end balances, not cumulative.

Show table:Balance sheet
Item2019Q42020Q42021Q42022Q22022Q42023Q22023Q42024Q22024Q42025Q22025Q4
Current assets110 283 196 169 148 126 99.4 117 99.1
Total assets132 320 244 223 206 181 155 178 163
Current liabilities21.6 28.6 26.8 31.6 35.6 28.6 26.8 34.5 50.5
Total liabilities31.6 44.8 43.7 51.5 54.7 59.6 58.8 101 116
Equity22.3 101 275 228 200 172 151 121 96.5 76.7 47.1
Cash flow
Quarterly · In mn (USD)
Operating -16.9 mn Investing -6.08 mn Financing -2.37 mn
2019Q4 2020Q4 2021Q4 2022Q2 2022Q4 2023Q2 2023Q4 2024Q2 2024Q4 2025Q2 2025Q4

Positive = cash in, negative = cash out.

Show table:Cash flow statement
Item2019Q42020Q42021Q42022Q22022Q42023Q22023Q42024Q22024Q42025Q22025Q4
Operating-31.7 -31.7 -57.9 -36.9 -33.1 -25.1 -23.5 -23.8 -19.0 -19.0 -16.9
Investing-3.03 -24.3 -56.9 26.7 15.3 12.7 -4.35 -3.91 -4.26 -2.59 -6.08
Financing-1.02 107 238 -0.18 -1.39 -1.55 -1.26 12.8 -1.17 32.5 -2.37
Cash at period end18.1 74.6 193 179 161 149 123 105 80.2 94.8 70.3
Profitability
Quarterly · %
Gross margin 67.0% Operating margin -88.4% Net margin -95.2%
2019Q4 2020Q4 2021Q4 2022Q2 2022Q4 2023Q2 2023Q4 2024Q2 2024Q4 2025Q2 2025Q4

Gross, operating and net margin = the respective profit ÷ revenue.

Show table:Profitability
Item2019Q42020Q42021Q42022Q22022Q42023Q22023Q42024Q22024Q42025Q22025Q4
Gross margin70.3%62.3%62.4%65.3%67.6%66.7%69.5%68.2%67.8%67.0%67.0%
Operating margin-131.6%-176.7%-206.4%-154.7%-133.2%-106.4%-94.9%-97.7%-100.9%-88.4%
Net margin-133.2%-138.5%-182.1%-211.6%-148.9%-142.1%-113.6%-96.1%-100.0%-122.3%-95.2%
Returns & leverage
Quarterly · %
ROE -111.2% ROA -59.8% Debt ratio 71.1%
2019Q4 2020Q4 2021Q4 2022Q2 2022Q4 2023Q2 2023Q4 2024Q2 2024Q4 2025Q2 2025Q4

ROE / ROA = trailing four-quarter net income ÷ average equity / total assets (annual mode: the year’s net income ÷ average of opening and closing). Not computed when the denominator is zero or negative.

Show table:Returns & leverage
Item2019Q42020Q42021Q42022Q22022Q42023Q22023Q42024Q22024Q42025Q22025Q4
ROE-75.2%-157.4%-115.4%-56.8%-63.9%-72.9%-87.8%-111.2%
ROA-71.8%-88.4%-46.1%-61.7%-54.1%-54.4%-59.8%
Debt ratio23.9%14.0%17.9%23.1%26.5%32.9%37.9%56.8%71.1%
EPS
Quarterly · US$
EPS US$-0.58
2019Q4 2020Q4 2021Q4 2022Q2 2022Q4 2023Q2 2023Q4 2024Q2 2024Q4 2025Q2 2025Q4
Show table:EPS
Item2019Q42020Q42021Q42022Q22022Q42023Q22023Q42024Q22024Q42025Q22025Q4
EPS(US$)-0.93-1.33-0.39-0.58-0.33-0.58-0.23-0.51-0.33-0.58

Source: SEC EDGAR (XBRL company facts)

Annual reports by year

20-F: annual report of a foreign private issuer. Filings are the original documents hosted on SEC EDGAR — this site neither mirrors nor edits them.

FAQ

Where can I read SOPHiA GENETICS SA (SOPH) annual reports?

Every year in the table above links straight to the full text on SEC EDGAR. US annual reports are web pages (HTML) rather than PDFs, so you can read and search them in the browser without downloading anything. 3 filings are currently indexed.

What is the difference between a 10-K and a 20-F?

A 10-K is the annual report of a US domestic issuer, with sections fixed by law: Item 1 Business, Item 1A Risk Factors, Item 7 Management's Discussion and Analysis. A 20-F is filed by foreign private issuers — Taiwanese companies with US ADRs, such as TSMC, file 20-F rather than 10-K. A 40-F applies to Canadian issuers under the MJDS.

Are earnings call materials available here?

No. Earnings calls are not SEC filings, so US pages on this site cover annual reports only. Taiwan has a mandatory investor-conference disclosure regime, and those materials are indexed under Annual Reports.

Source: US Securities and Exchange Commission (SEC) EDGAR. This site indexes public filings and links to them; it hosts no copies, offers no investment advice, and makes no warranty as to timeliness or completeness.
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